The most paramount issue that has become concerning to scholars, observers, researchers, writers, international organizations like Transparency International and medias is the matter of corruption, therefore this paper discussed the factors that lead to widespread of corruption in Khartoum- Sudan-. the approach of this paper is descriptive and qualitative method. In order to collect data and information the researcher used secondary data sources such as: books, references, articles, newspapers, internet and reports in addition to other documents that related to the subject. To analyse the data, the investigator used NVivo 12 Plus, using crosstab, matrix and cluster analysis. The feedback of this paper is examining of four main factors that lead to widespread corruption in Khartoum- Sudan namely: Absences of the rule of law, weakness of Judiciary, Lack of political opposition and weakness of civil society organizations. In order to curb the corruption in Khartoum -Sudan- the rule of law must activate, Judiciary must be independent, freedom for civil society organizations to create bodies that observe the act of the government and liberty to the political oppositions to play their role.